TBI Core: Harmonized
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Protocols
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Variables
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In this harmonized study, data from the CENTER-TBI project is harmonized with data from affiliate research projects in India and Australia, collected according to the same CRF.
CENTER-TBI aims to advance the care for patients with traumatic brain injury (TBI), a field in medicine with one of the greatest unmet needs. It is a large-scale project (FP7 grant 602150) aiming to improve characterization of TBI in order to facilitate individualized treatments and identify the most effective clinical care, providing high quality evidence in support of treatment recommendations and guidelines.
The CENTER-TBI Core study collected high quality clinical and epidemiological data with repositories for neuro-imaging, DNA, and serum from over 4500 patients with TBI in 19 countries in Europe and Israel. Enrolment was in three strata, differentiated by care path: (1) patients discharged home from the emergency room (ER stratum); (2) patients admitted to hospital, but not to the intensive care unit (admission stratum); (3) patients admitted to the Intensive Care Unit (ICU stratum). It includes long-term outcome up to 24 months after injury.